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Article

NF-kB action in sepsis: the innate immune system and the heart

1 Jan 2004

Abstract excerpt

Sepsis is the clinical syndrome that results from a host's inflammatory response to infection via activation of the innate immune system. This response involves a complex network of inflammatory mediators that is self-reinforcing. When this immune response progresses uncontrollably, it can ultimately result in cardiovascular collapse and death. This complex inflammatory response is comprised of multiple mediators...

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Identifiers

PMID: 14977537
DOI: 10.2741/1304

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