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Article

Necroptosis in sepsis: Mechanisms and therapeutic potential

24 Jun 2025

Abstract excerpt

Sepsis, a life-threatening condition characterized by systemic inflammatory responses, remains a significant challenge in clinical settings due to its complex pathogenesis and limited therapeutic strategies. Central to this conundrum is the role of cell death mechanisms, particularly necroptosis, in the progression and resolution of sepsis. Necroptosis, a regulated form of necrotic cell death, not only...

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PMID: 40603202
DOI: 10.1016/j.cytogfr.2025.06.008

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