Article
Calpain 10 gene polymorphisms and the risk of ischaemic stroke in a Polish population.
Przeglad lekarski - 1 Jan 2003
Małecki Maciej T, Słowik Agnieszka, Sado Małgorzata, Turaj Wojciech, Klupa Tomasz, Sieradzki Jacek, Szczudlik Andrzej
Abstract excerpt
Experimental studies showed that calpain inhibitors suppressed post-ischaemic changes in the brain. We examined whether an association exists between variants of three single nucleotide polymorphisms (SNPs) -43, -19, and -63 in the calpain 10 gene and either stroke or size of ischaemic lesions on the CT in a Polish population. We included 209 patients with a first ischaemic stroke and 148 controls. The patients...
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