Article
Absence of association between polymorphisms in the hemostatic factor pathway genes and carotid intimal medial thickness: the Framingham Heart Study.
Stroke - 1 Mar 2004
Fox Caroline S, Larson Martin G, Corey Diane, Feng DaLi, Lindpaintner Klaus, Polak Joseph F, Wolf Philip A, D'Agostino Ralph B, Tofler Geoffrey H, O'Donnell Christopher J
Abstract excerpt
BACKGROUND AND PURPOSE: Fibrinogen, plasminogen activator inhibitor-1, and other key proteins in the coagulation cascade have been implicated in the origin of cardiovascular disease. Polymorphisms in genes encoding these proteins have been associated with variability in plasma levels of these proteins. Carotid intimal medial thickness (IMT) is a heritable, quantitative measure of atherosclerosis that is...
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