Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity patterns in the SR-BI/II locus can be explained by a recent selective sweep.

Molecular biology and evolution - 1 Apr 2004

Le Jossec Mireille, Wambach Tina, Labuda Damian, Sinnett Daniel, Levy Emile

Abstract excerpt

The human scavenger receptor class B type I (SR-BI and splice variant SR-BII) plays a central role in HDL cholesterol metabolism and represents a candidate gene for a number of related diseases. We examined the genetic diversity of its coding and flanking regions in a sample of 178 chromosomes from individuals of European, African, East Asian (including Southeast Asian), Middle-Eastern as well as Amerindian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Geography
Share to CD36 Antigens
Share to DNA Fingerprinting

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lysosomal Membrane Proteins

Share to Receptors, Immunologic

Share to Receptors, Scavenger

Share to Scavenger Receptors, Class B

Share to Sialoglycoproteins

Source

Identifiers

PMID: 14963100
DOI: 10.1093/molbev/msh074

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity patterns in the SR-BI/II locus can be explained by a recent selective sweep.PMID 14963100Read ↗

Population-based study of SR-BI genetic variation and lipid profile.Semantic proximity Read ↗

Genetic diversity of the <i>LILRB1</i> and <i>LILRB2</i> coding regions in an admixed Brazilian population sampleSemantic proximity Read ↗

Phylogeny of human beta-globin haplotypes and its implications for recent human evolution.Semantic proximity Read ↗

Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits.Semantic proximity Read ↗

Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.Semantic proximity Read ↗

A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes.Semantic proximity Read ↗

SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex.Semantic proximity Read ↗

Association of Polymorphisms at the SR-BI Gene Locus With Plasma Lipid Levels and Body Mass Index in a White PopulationSemantic proximity Read ↗

Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species.Semantic proximity Read ↗

Identification of the ancestral haplotype for apolipoprotein B suggests an African origin of Homo sapiens sapiens and traces their subsequent migration to Europe and the Pacific.Semantic proximity Read ↗

Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease.Semantic proximity Read ↗

Advantageous diversity maintained by balancing selection in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.