Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.

doi:10.1086/344513

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.

American journal of human genetics - 1 Dec 2002

Stead John D H, Jeffreys Alec J

Abstract excerpt

The insulin minisatellite (INS VNTR) associates with susceptibility to a variety of diseases. We have developed a high-resolution system for analyzing variant repeat distributions applicable to all known minisatellite alleles, irrespective of size, which allows lineages of related alleles to be identified. This system has previously revealed extremely low structural diversity in the minisatellite among northern...

Topics

Africa
Alleles
Animals
Black People
Gene Frequency
Genetic Variation
Genetics, Population
Humans
Insulin
Kinetics
Minisatellite Repeats
Mutation
Primates
United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 12404181
DOI: 10.1086/344513
PMCID: PMC378563

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics