Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.

American journal of human genetics - 1 Dec 2002

Stead John D H, Jeffreys Alec J

Abstract excerpt

The insulin minisatellite (INS VNTR) associates with susceptibility to a variety of diseases. We have developed a high-resolution system for analyzing variant repeat distributions applicable to all known minisatellite alleles, irrespective of size, which allows lineages of related alleles to be identified. This system has previously revealed extremely low structural diversity in the minisatellite among northern...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Africa
Share to Black People
Share to Genetics, Population

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Insulin

Share to Kinetics

Share to Minisatellite Repeats

Share to Primates

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 12404181
DOI: 10.1086/344513
PMCID: PMC378563

Genes

INS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Structural analysis of insulin minisatellite alleles reveals unusually large differences in diversity between Africans and non-Africans.PMID 12404181Read ↗

Global haplotype diversity in the human insulin gene region.Semantic proximity Read ↗

Minisatellite diversity supports a recent African origin for modern humans.Semantic proximity Read ↗

Larger genetic differences within africans than between Africans and Eurasians.Semantic proximity Read ↗

Genetic variation among world populations: inferences from 100 Alu insertion polymorphisms.Semantic proximity Read ↗

Influence of allele lineage on the role of the insulin minisatellite in susceptibility to type 1 diabetes.Semantic proximity Read ↗

Haplotypes in the dystrophin DNA segment point to a mosaic origin of modern human diversity.Semantic proximity Read ↗

The genetic structure of human populations studied through short insertion-deletion polymorphisms.Semantic proximity Read ↗

Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans.Semantic proximity Read ↗

The Italian genome reflects the history of Europe and the Mediterranean basin.Semantic proximity Read ↗

A highly variable segment of human subterminal 16p reveals a history of population growth for modern humans outstide Africa.Semantic proximity Read ↗

The KIR repertoire of a West African chimpanzee population is characterized by limited gene, allele, and haplotype variation.Semantic proximity Read ↗

Biology and applications of human minisatellite loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.