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Article

Origins, lineage-specific expansions, and multiple losses of tyrosine kinases in eukaryotes.

Molecular biology and evolution - 1 May 2004

Shiu Shin-Han, Li Wen-Hsiung

Abstract excerpt

Tyrosine kinases are important components of metazoan signaling pathways, and their mutant forms are implicated in various malignancies. Searching the sequences from the genomes of 28 eukaryotes and the GenBank, we found tyrosine kinases not only in metazoans but also in the green algae Chlamydomonas reinhardtii, the potato late blight pathogen Phytophthora infestans, and the protozoan pathogen Entamoeba...

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Identifiers

PMID: 14963097
DOI: 10.1093/molbev/msh077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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