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Article

Protein tyrosine phosphatases: counting the trees in the forest.

Gene - 28 Dec 1998

Hooft van Huijsduijnen R

Abstract excerpt

The recent identification of many different protein tyrosine phosphatases (PTPs) has led to the recognition that these enzymes match protein tyrosine kinases (PTKs) in importance for intracellular signalling. The total number of PTPs encoded by the mammalian genome has been estimated at between 500 and approx. 2000. These estimates are imprecise due to the large number of sequence database entries that represent...

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PMID: 9931406
DOI: 10.1016/s0378-1119(98)00513-7

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