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Article

Growth and characterization of fibroblasts obtained from bronchoalveolar lavage of patients with scleroderma.

The Journal of rheumatology - 1 Nov 1992

Ludwicka A, Trojanowska M, Smith E A, Baumann M, Strange C, Korn J H, Smith T, Leroy E C, Silver R M

Abstract excerpt

We describe the detection and the growth of fibroblasts with human smooth muscle cell differentiation features from bronchoalveolar lavage (BAL) fluid of 53% of patients with scleroderma, but not from healthy controls. The binding of alpha-actin, vimentin and desmin antibodies by scleroderma lung fibroblasts exceeded that of normal adult lung fibroblasts, indicating that scleroderma lung fibroblasts express some...

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PMID: 1491389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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