Article
Growth and characterization of fibroblasts obtained from bronchoalveolar lavage of patients with scleroderma.
The Journal of rheumatology - 1 Nov 1992
Ludwicka A, Trojanowska M, Smith E A, Baumann M, Strange C, Korn J H, Smith T, Leroy E C, Silver R M
Abstract excerpt
We describe the detection and the growth of fibroblasts with human smooth muscle cell differentiation features from bronchoalveolar lavage (BAL) fluid of 53% of patients with scleroderma, but not from healthy controls. The binding of alpha-actin, vimentin and desmin antibodies by scleroderma lung...
Topics
- Actins
- Adult
- Antibodies
- Blotting, Northern
- Bronchoalveolar Lavage Fluid
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Collagen
- Cytoskeletal Proteins
- Desmin
- Female
- Fibroblasts
- Fibronectins
- Humans
- Male
- Middle Aged
- Muscle, Smooth