Article
Association of transforming growth factor beta1 and tumor necrosis factor alpha polymorphisms with anti-SSB/La antibody secretion in patients with primary Sjögren's syndrome.
Arthritis and rheumatism - 1 Feb 2004
Gottenberg Jacques-Eric, Busson Marc, Loiseau Pascale, Dourche Monique, Cohen-Solal Julien, Lepage Virginia, Charron Dominique, Miceli Corinne, Sibilia Jean, Mariette Xavier
Abstract excerpt
OBJECTIVE: To determine whether cytokine gene polymorphisms of interferon-gamma (IFNgamma), interleukin-6 (IL-6), IL-10, tumor necrosis factor alpha (TNFalpha), and transforming growth factor beta1 (TGFbeta1) predispose subjects to the development of primary Sjögren's syndrome (SS). METHODS: Single-base-exchange cytokine gene polymorphisms were analyzed in 129 French patients with primary SS who fulfilled the...
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