Article
Genetic polymorphisms of TGF-beta1 & TNF-beta and breast cancer risk.
Breast cancer research and treatment - 1 Mar 2005
Lee Kyoung-Mu, Park Sue Kyung, Hamajima Nobuyuki, Tajima Kazuo, Yoo Keun-Young, Shin Aesun, Noh Dong-Young, Ahn Sei-Hyun, Hirvonen Ari, Kang Daehee
Abstract excerpt
OBJECTIVE: The proliferation of malignant breast epithelial cells is regulated by various stimuli including cytokines and growth factors, thus the variants of those genes may modify the breast cancer risk. To evaluate the potential influences of TGF-beta1 T29C and TNF-beta A252G gene polymorphisms on breast cancer risk, a case-control study was conducted in Korea. METHODS: Histologically confirmed breast cancer...
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