Article
Ensuring the consistency of rDNA-derived biologicals: the contribution of gene sequencing.
Developments in biological standardization - 1 Jan 1994
Griffiths E
Abstract excerpt
The past few years have seen an interesting debate on the extent to which DNA-sequencing of expression systems is appropriate as a basis for assessing the quality and consistency of rDNA-derived products. While there is a need to improve and validate the ability of end-product testing procedures...
Topics
- Biological Products
- DNA, Recombinant
- Genetic Variation
- Mutation
- Protein Biosynthesis
- Protein Processing, Post-Translational
- Quality Control
- Recombinant Proteins
- Sequence Analysis, DNA