Article
Genetic stability of protein expression systems in yeast.
Developments in biological standardization - 1 Jan 1994
Bussineau C M, Shuster J R
Abstract excerpt
For the expression of recombinant proteins in yeast, genetic stability is monitored using a combination of standard microbiology and nucleic acid testing procedures. Process consistency during the cell amplification and product expression phases of fermentation are also reliable indicators of sta...
Topics
- Biotechnology
- DNA, Recombinant
- Gene Expression
- Genetic Markers
- Mutation
- Phenotype
- Plasmids
- Quality Control
- Recombinant Proteins
- Recombination, Genetic
- Saccharomyces cerevisiae