Article
Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1.
FEBS letters - 11 Feb 2003
Heyninck Karen, Kreike Marja M, Beyaert Rudi
Abstract excerpt
Nuclear factor kappa B (NF-kappa B)-dependent gene expression plays an important role in numerous cellular processes including stress responses, inflammation and cell proliferation. Therefore, the activity of this transcription factor needs to be tightly regulated. Among others, the NF-kappa B-dependent zinc finger protein A20 is involved in the negative feedback regulation of NF-kappa B activation in response to...
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