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Article

Activation of NF-kappaB and STAT3 in rat oval cells during 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration.

Hepatology (Baltimore, Md.) - 1 Feb 2004

Sánchez Aránzazu, Factor Valentina M, Schroeder Insa S, Nagy Peter, Thorgeirsson Snorri S

Abstract excerpt

Proliferation and differentiation of hepatic stem cell progenies (i.e., oval cells) sustain liver regeneration when the replicative and functional capacity of hepatocytes is impaired. The signaling pathways that control stem cell activation remain poorly understood. In this study, we investigated...

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Source

Identifiers

PMID: 14767990
DOI: 10.1002/hep.20040

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14767990-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Activation of NF-kappaB and STAT3 in rat oval cells during 2-acetylaminofluorene/partial hepatectomy-induced liver regeneration.PMID 14767990Read ↗

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Differential hepatic stem cell proliferation and differentiation after partial hepatectomy in rats.Semantic proximity Read ↗

Activation, isolation, identification and culture of hepatic stem cells from porcine liver tissues.Semantic proximity Read ↗

Hepatocyte growth factor accelerates the proliferation of hepatic oval cells and possibly promotes the differentiation in a 2‐acetylaminofluorene/partial hepatectomy model in ratsSemantic proximity Read ↗

Differentiation processes of oval cells into hepatocytes: proposals based on morphological and phenotypical traits in carcinogen-treated hamster liver.Semantic proximity Read ↗

Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1.Semantic proximity Read ↗

Putative liver progenitor cells: conditions for long-term survival in culture.Semantic proximity Read ↗

Hepatic progenitor cells in human fetal liver express the oval cell marker Thy-1Semantic proximity Read ↗

Bmi1 Is Required for Hepatic Progenitor Cell Expansion and Liver Tumor DevelopmentSemantic proximity Read ↗

NF-κB essential modifier is required for hepatocyte proliferation and the oval cell reaction after partial hepatectomy in mice.Semantic proximity Read ↗

Flow cytometry and monoclonal antibodies identify normal liver cell populations antigenically related to oval cells.Semantic proximity Read ↗

Hepatocyte nuclear factor 4α induces a tendency of differentiation and activation of rat hepatic stellate cells.Semantic proximity Read ↗

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