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Article

Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1.

The American journal of pathology - 1 Jul 2003

Shimano Koichi, Satake Makoto, Okaya Atsuhito, Kitanaka Junichi, Kitanaka Nobue, Takemura Motohiko, Sakagami Masafumi, Terada Nobuyuki, Tsujimura Tohru

Abstract excerpt

Organ-specific stem cells can be identified by the side population (SP) phenotype, which is defined by the property to effectively exclude the Hoechst 33342 dye. The ATP-binding cassette transporter ABCG2/BCRP1 mediates the SP phenotype. Because hepatic oval cells possess several characteristics...

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Source

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Identifiers

PMID: 12819005
DOI: 10.1016/S0002-9440(10)63624-3
PMCID: PMC1868160

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12819005-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1.PMID 12819005Read ↗

Erythroblasts highly express the ABC transporter Bcrp1/ABCG2 but do not show the side population (SP) phenotype.Semantic proximity Read ↗

Ocular surface epithelia contain ABCG2-dependent side population cells exhibiting features associated with stem cells.Semantic proximity Read ↗

Role of the ATP-binding cassette transporter Abcg2 in the phenotype and function of cardiac side population cells.Semantic proximity Read ↗

Identification of side population cells in chicken embryonic gonads.Semantic proximity Read ↗

Human limbal epithelium contains side population cells expressing the ATP-binding cassette transporter ABCG2.Semantic proximity Read ↗

Characterization of a Side Population of Cancer Cells from Human Gastrointestinal SystemSemantic proximity Read ↗

Side population cells derived from adult human liver generate hepatocyte-like cells in vitro.Semantic proximity Read ↗

Side Population: Its Use in the Study of Cellular Heterogeneity and as a Potential Enrichment Tool for Rare Cell PopulationsSemantic proximity Read ↗

Remarkable heterogeneity displayed by oval cells in rat and mouse models of stem cell-mediated liver regeneration.Semantic proximity Read ↗

Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties.Semantic proximity Read ↗

Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice.Semantic proximity Read ↗

Age-Dependent Increase in Side Population Distribution Within Hematopoiesis: Implications for Our Understanding of the Mechanism of AgingSemantic proximity Read ↗

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