Article
Role of an internal ribosome entry site in the translational control of the human transcription factor Sp3.
International journal of oncology - 1 Mar 2004
Hernandez Eric Moore, Chan Connie H, Xu Biying, Notario Vicente, Richert John R
Abstract excerpt
Sp1 and Sp3 are transcription factors involved in the regulation of numerous genes involved in oncogenesis. Sp3 is a bi-functional transcription factor with three different isoforms. Its bi-functional activity may in part be regulated by the relative expression of these isoforms. Northern blot analysis of Sp3 detects only a single transcript. Analysis of the known Sp3 cDNA sequence shows a high GC content and...
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