Article
Gene-gene and gene-environmental interactions of p53, p21, and IRF-1 polymorphisms in Korean women with cervix cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Jan 2000
Lee J E, Lee S J, Namkoong S E, Um S J, Sull J W, Jee S H, You Y K, Park J S
Abstract excerpt
BACKGROUND: The aim of this study was to identify gene-gene and gene-environmental factors affecting cervix carcinogenesis in Korean women. METHODS: We evaluated 530 subjects composed of 185 female cervix cancer patients and 345 normal healthy women. The single nucleotide polymorphisms (SNPs) of p53 codon 72, p21 codon 31, and interferon regulatory factor-1 (IRF-1) intron 6 were evaluated from extracted DNA of...
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