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Article

Polymorphisms in an interferon-gamma receptor-1 gene marker and susceptibility to periodontitis.

Acta odontologica Scandinavica - 1 Oct 2003

Fraser David A, Loos Bruno G, Boman Ulf, van Winkelhoff Arie Jan, van der Velden Ubele, Schenck Karl, Dembic Zlatko

Abstract excerpt

Chronic marginal periodontitis is an inflammatory condition in which the supporting tissues of the teeth are destroyed. Interferon (IFN)-gamma is a cytokine that plays a pivotal role in the defense against infection, and mutations in the gene coding for the ligand binding chain (alpha, R1) of the IFN-gamma receptor (IFNGR1) confer suseptibility on infections caused by poorly virulent mycobacteria. Using an...

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Identifiers

PMID: 14763782
DOI: 10.1080/00016350310006168

Genes

IFNGR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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