Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.

Journal of neurochemistry - 1 Feb 2004

Ohsawa Keiko, Imai Yoshinori, Sasaki Yo, Kohsaka Shinichi

Abstract excerpt

Ionized calcium binding adaptor molecule 1 (Iba1) is a microglia/macrophage-specific calcium-binding protein. Iba1 has the actin-bundling activity and participates in membrane ruffling and phagocytosis in activated microglia. In order to understand the Iba1-related intracellular signalling pathwa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Surface
Share to Avian Proteins
Share to Basigin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Proteins

Share to Egtazic Acid

Share to Macrophage Colony-Stimulating Factor

Share to Microglia

Share to Microinjections

Source

Identifiers

PMID: 14756805
DOI: 10.1046/j.1471-4159.2003.02213.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14756805-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microglia/macrophage-specific protein Iba1 binds to fimbrin and enhances its actin-bundling activity.PMID 14756805Read ↗

Involvement of Iba1 in membrane ruffling and phagocytosis of macrophages/microglia.Semantic proximity Read ↗

Iba1 is an actin-cross-linking protein in macrophages/microglia.Semantic proximity Read ↗

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation.Semantic proximity Read ↗

Role of calcium-dependent actin-bundling proteins: characterization of Dictyostelium mutants lacking fimbrin and the 34-kilodalton protein.Semantic proximity Read ↗

Phagocytosis: receptors, signal integration, and the cytoskeleton.Semantic proximity Read ↗

Anaplasma phagocytophilum Hijacks Flotillin and NPC1 Complex To Acquire Intracellular Cholesterol for Proliferation, Which Can Be Inhibited with EzetimibeSemantic proximity Read ↗

Calcium-binding protein EhCaBP3 is recruited to the phagocytic complex ofEntamoeba histolyticaby interacting with Arp2/3 complex subunit 2Semantic proximity Read ↗

Calcium and calmodulin-dependent serine/threonine protein kinase type II (CaMKII)-mediated intramolecular opening of integrin cytoplasmic domain-associated protein-1 (ICAP-1α) negatively regulates β1 integrins.Semantic proximity Read ↗

Altered synaptic connectivity and brain function in mice lacking microglial adapter protein Iba1Semantic proximity Read ↗

RNAi Library Screening Reveals Gβ1, Casein Kinase 2α and ICAP-1 as Novel Regulators of LFA-1-mediated T-cell Polarity and MigrationSemantic proximity Read ↗

RNAi Library Screening Reveals Gβ 1 , Casein Kinase 2α and ICAP-1 as Novel Regulators of LFA-1-mediated T-cell Polarity and MigrationSemantic proximity Read ↗

Homotypic dimerization of the actin-binding protein p57/coronin-1 mediated by a leucine zipper motif in the C-terminal region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.