Article
A genome-wide scan for loci predisposing to non-syndromic cleft lip with or without cleft palate in two large Syrian families.
American journal of medical genetics. Part A - 1 Dec 2003
Wyszynski Diego F, Albacha-Hejazi Hasan, Aldirani Mohammed, Hammod Moustafa, Shkair Hikmat, Karam Ahmed, Alashkar Jehad, Holmes Taura N, Pugh Elizabeth W, Doheny Kimberly F, McIntosh Iain, Beaty Terri H, Bailey-Wilson Joan E
Abstract excerpt
Non-syndromic cleft lip with/without cleft palate (CL/P) is a common, usually non-fatal birth defect of complex etiology. Several segregation analyses have demonstrated that genetic factors are important in the pathogenesis of CL/P, most likely through the interaction of several genes of modest e...
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