Article
CALCYON gene variation, schizophrenia, and cocaine dependence.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Feb 2004
Luo Xingguang, Kranzler Henry, Lappalainen Jaakko, Rosenheck Robert, Charney Dennis, Zuo Lingjun, Erdos Joseph, van Kammen Daniel P, Gelernter Joel
Abstract excerpt
Calcyon is a brain-specific D1 dopamine receptor-interacting protein, with a potential role in D1-mediated physiological processes, including motor control, reward mechanisms, and cognitive processes. Our objective was to investigate the relationship between polymorphism of the CALCYON gene and (1) schizophrenia and (2) cocaine dependence in African-American (AA) and European-American (EA) subjects. Two single...
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