Article
Variation in M protein production among Streptococcus pyogenes strains according to emm genotype.
Microbiology and immunology - 1 Jun 2011
Matsumoto Masakado, Suzuki Masahiro, Hirose Kaoru, Hiramatsu Reiji, Minagawa Hiroko, Minami Masaaki, Tatsuno Ichiro, Okamoto Akira, Ohta Michio, Hasegawa Tadao
Abstract excerpt
M protein is an important virulence determinant in Streptococcus pyogenes, but the amounts of M protein in various strains of the species remain to be elucidated. To assess the amount of M protein in strains of each emm genotype, dot blot analysis was performed on 141 clinically isolated strains. Among the cell membrane-associated proteins, M protein was present in greater quantities in the emm1, 3, and 6 strains...
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