Role of the conserved C-repeat region of the M protein of Streptococcus pyogenes.

doi:10.1111/j.1365-2958.1995.tb02360.x

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Article

Role of the conserved C-repeat region of the M protein of Streptococcus pyogenes.

Molecular microbiology - 1 Mar 1995

Perez-Casal J, Okada N, Caparon M G, Scott J R

Abstract excerpt

The surface-located M protein functions to protect Streptococcus pyogenes (the group A streptococcus) from phagocytosis by polymorphonuclear leukocytes. It has been suggested that this protection results from the ability of M protein to bind factor H, a serum protein that can inhibit the activation of complement. Among different serological variants of M protein, the C-repeat domain is highly conserved and is...

Topics

Alleles
Amino Acid Sequence
Antigens, Bacterial
Bacterial Adhesion
Bacterial Outer Membrane Proteins
Bacterial Proteins
Base Sequence
Carrier Proteins
Cloning, Molecular
Complement Factor H
Conserved Sequence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Deletion

Keratinocytes

Molecular Sequence Data

Mutagenesis

Phagocytosis

Repetitive Sequences, Nucleic Acid

Streptococcus pyogenes

Source

Open in PubMed

Identifiers

PMID: 7596292
DOI: 10.1111/j.1365-2958.1995.tb02360.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7596292-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Role of the conserved C-repeat region of the M protein of Streptococcus pyogenes.PMID 7596292Read ↗

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