Article
Primitive hematopoietic stem cells shows a polyclonal pattern in myelodysplastic syndromes.
Haematologica - 1 Jan 2004
Guidetti Francesca, Grazioli Sandra, Capelli Francesca, Marini Claudia, Gallicchio Margherita, De Micheli Daniela, Castello Luigi, Sainaghi Pier Paolo, Fra Gian Paolo, Saglio Giuseppe, Avanzi Gian Carlo
Abstract excerpt
BACKGROUND AND OBJECTIVES: Clonal hematopoiesis is the hallmark of myelodysplastic syndromes, but the role played by pluripotent stem cells and progenitor cells in these disorders remains unclear. DESIGN AND METHODS: Eight female patients with myelodysplastic syndrome were studied. X-chromosome i...
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