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Article

Acute leukemia after a primary myelodysplastic syndrome: immunophenotypic, genotypic, and clinical characteristics.

Blood - 1 Aug 1991

San Miguel J F, Hernández J M, González-Sarmiento R, González M, Sánchez I, Orfao A, Cañizo M C, López Borrasca A

Abstract excerpt

We studied the nature of blast cells in 41 patients with acute leukemia following a previous primary myelodysplastic syndrome (MDS) by a combined multiparameter analysis including morphologic, immunophenotypic, and molecular genetic (Igs, T-cell receptor (TCR)-beta, -gamma, and -delta and the major breakpoint cluster region [M-bcr]) investigations. In addition, the clinical and hematologic characteristics...

Topics

Acute Disease
Aged
Biomarkers
Bone Marrow
DNA, Neoplasm
Genes, Immunoglobulin
Genotype
Humans
Immunoglobulin Constant Regions
Immunophenotyping
Leukemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Myelodysplastic Syndromes

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Identifiers

PMID: 1859889

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1859889-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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