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Article

Immunoassay for wild-type protein in lymphocytes predicts germline mutations in patients at risk for hereditary colorectal cancer.

The Journal of laboratory and clinical medicine - 1 Jan 2004

Fields Jeremy Z, Gao Zhiping, Gao Zhenqiang, Lewis Marcia, Maimonis Peter, Harvey Jean, Lynch Henry T, Boman Bruce M

Abstract excerpt

Using colorectal cancer (CRC) as an example, we present the hypothesis that quantitative immunoassays for wild-type (full-length) proteins can be used to identify carriers of traits for hereditary diseases. In the case of hereditary CRC, this involves identifying individuals with germline mutatio...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14749686
DOI: 10.1016/j.lab.2003.10.001

Genes

APC
MLH1
MSH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14749686-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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