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Article

Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians.

Diabetes - 1 Feb 2004

Gu Harvest F, Abulaiti Adili, Ostenson Claes-Göran, Humphreys Keith, Wahlestedt Claes, Brookes Anthony J, Efendic Suad

Abstract excerpt

Adiponectin (APM1) is an adipocyte-derived peptide. The APM1 gene is located on chromosome 3q27 and linked to type 2 diabetes. In patients with type 2 diabetes, the adiponectin level in plasma is decreased in comparison to healthy subjects. To identify genetic defects of the APM1 gene that contri...

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Source

Identifiers

PMID: 14749263
DOI: 10.2337/diabetes.53.2007.s31

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14749263-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Research trail→

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Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians.PMID 14749263Read ↗

Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians.Semantic proximity Read ↗

Genetics of the APM1 locus and its contribution to type 2 diabetes susceptibility in French Caucasians.Semantic proximity Read ↗

Identification of a regulatory single nucleotide polymorphism in the adiponectin (APM1) gene associated with type 2 diabetes in Han nationality.Semantic proximity Read ↗

Multigenic control of serum adiponectin levels: evidence for a role of the APM1 gene and a locus on 14q13.Semantic proximity Read ↗

Haplotypes in the promoter region of the ADIPOQ gene are associated with increased diabetes risk in a German Caucasian population.Semantic proximity Read ↗

Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.Semantic proximity Read ↗

Genetic analysis of adiponectin and obesity in Hispanic families: the IRAS Family Study.Semantic proximity Read ↗

Linkage of plasma adiponectin levels to 3q27 explained by association with variation in the APM1 gene.Semantic proximity Read ↗

The +276 polymorphism of the APM1 gene, plasma adiponectin concentration, and cardiovascular risk in diabetic men.Semantic proximity Read ↗

Single Nucleotide Polymorphisms in exon 3 of the adiponectin gene in subjects with type 2 diabetes mellitus.Semantic proximity Read ↗

Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians.Semantic proximity Read ↗

The adiponectin gene is associated with adiponectin levels but not with characteristics of the insulin resistance syndrome in healthy Caucasians.Semantic proximity Read ↗

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