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Article

Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.

Journal of virology - 1 Feb 2004

Everett Roger D, Boutell Chris, Orr Anne

Abstract excerpt

Herpes simplex virus type 1 (HSV-1) immediate-early (IE) regulatory protein ICP0 is required for efficient progression of infected cells into productive lytic infection, especially in low-multiplicity infections of limited-passage human fibroblasts. We have used single-cell-based assays that allow detailed analysis of the ICP0-null phenotype in low-multiplicity infections of restrictive cell types. The major...

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Identifiers

PMID: 14747541
DOI: 10.1128/jvi.78.4.1763-1774.2004
PMCID: PMC369471

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phenotype of a herpes simplex virus type 1 mutant that fails to express immediate-early regulatory protein ICP0.PMID 14747541Read ↗

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