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Article

Identification of a novel sequence in PDZ-RhoGEF that mediates interaction with the actin cytoskeleton.

Molecular biology of the cell - 1 Apr 2004

Banerjee Jayashree, Wedegaertner Philip B

Abstract excerpt

Small GTPases of the Rho family are crucial regulators of actin cytoskeleton rearrangements. Rho is activated by members of the Rho guanine-nucleotide exchange factor (GEF) family; however, mechanisms that regulate RhoGEFs are not well understood. This report demonstrates that PDZ-RhoGEF, a member of a subfamily of RhoGEFs that contain regulator of G protein signaling domains, is partially localized at or near...

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Identifiers

PMID: 14742719
DOI: 10.1091/mbc.e03-07-0527
PMCID: PMC379273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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