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Article

Orally active fusion inhibitor of respiratory syncytial virus.

Antimicrobial agents and chemotherapy - 1 Feb 2004

Cianci Christopher, Yu Kuo-Long, Combrink Keith, Sin Ny, Pearce Bradley, Wang Alan, Civiello Rita, Voss Stacey, Luo Guangxiang, Kadow Kathy, Genovesi Eugene V, Venables Brian, Gulgeze Hatice, Trehan Ashok, James Jennifer, Lamb Lucinda, Medina Ivette, Roach Julia, Yang Zheng, Zadjura Lisa, Colonno Richard, Clark Junius, Meanwell Nicholas, Krystal Mark

Abstract excerpt

BMS-433771 was found to be a potent inhibitor of respiratory syncytial virus (RSV) replication in vitro. It exhibited excellent potency against multiple laboratory and clinical isolates of both group A and B viruses, with an average 50% effective concentration of 20 nM. Mechanism-of-action studie...

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Source

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Identifiers

PMID: 14742189
DOI: 10.1128/AAC.48.2.413-422.2004
PMCID: PMC321540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14742189-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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