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Article

The role of the conserved histidine-aspartate pair in the 'base-off' binding of cobalamins.

Bioorganic & medicinal chemistry - 1 Feb 2004

Chen Hao-Ping, Lung Feng-Di, Yeh Chiu-Chang, Chen Hui-Lan, Wu Shih-Hsiug

Abstract excerpt

The conserved cobalamin-binding domain of glutamate mutase exists as a separate dissociable subunit, MutS. The results obtained from BIAcore analysis indicate that MutS alone, in the absence of E component of glutamate mutase (MutE, catalytic subunit), is capable of binding hydroxocobinamide (OHC...

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PMID: 14738967
DOI: 10.1016/j.bmc.2003.10.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14738967-2026-09-02.1. Manifest publication-graph-cohort-2026-09-02.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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