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Article

Y-box protein-associated acidic protein (YBAP1/C1QBP) affects the localization and cytoplasmic functions of YB-1.

Scientific reports - 18 Apr 2018

Matsumoto Ken, Kose Shingo, Kuwahara Iku, Yoshimura Mami, Imamoto Naoko, Yoshida Minoru

Abstract excerpt

The Y-box proteins are multifunctional nucleic acid-binding proteins involved in various aspects of gene regulation. The founding member of the Y-box protein family, YB-1, functions as a transcription factor as well as a principal component of messenger ribonucleoprotein particles (mRNPs) in somatic cells. The nuclear level of YB-1 is well correlated with poor prognosis in many human cancers. Previously, we...

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PMID: 29670170
DOI: 10.1038/s41598-018-24401-3
PMCID: PMC5906478

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