Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metastasis-associated protein 1 inhibits p53-induced apoptosis

1 Nov 2007

Abstract excerpt

Metastasis-associated protein 1 (MTA1) is highly upregulated in cancer cells with metastatic potential; however, the molecular mechanism by which MTA1 increases the metastatic potential of cancer cells is far from clear. We characterized the functional consequences of MTA1 overexpression on p53-induced apoptosis of cancer cells. MTA1 was associated with p53 in a co-immunoprecipitation assay. MTA1 also had...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Stress, Anesthesia, and Immune Response
Share to Histone Deacetylase Inhibitors Research
Share to Peptidase Inhibition and Analysis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17914590
DOI: 10.3892/or.18.5.1311

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 26 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metastasis-associated protein 1 inhibits p53-induced apoptosisPMID 17914590Read ↗

Tumor metastasis-associated human MTA1 gene and its MTA1 protein product: Role in epithelial cancer cell invasion, proliferation and nuclear regulationSemantic proximity Read ↗

MTA1 gene silencing inhibits invasion and alters the microRNA expression profile of human lung cancer cells.Semantic proximity Read ↗

Metastasis-Associated Protein 1/Nucleosome Remodeling and Histone Deacetylase Complex in CancerSemantic proximity Read ↗

RNA interference of metastasis‐associated gene 1 inhibits metastasis of B16F10 melanoma cells in a C57BL/6 mouse modelSemantic proximity Read ↗

[Activator of metastasis in cancer cells, Mst1/S100A4 protein binds to tumor suppressor protein p53].Semantic proximity Read ↗

Tumor metastasis-associated humanMTA1 gene: Its deduced protein sequence, localization, and association with breast cancer cell proliferation using antisense phosphorothioate oligonucleotidesSemantic proximity Read ↗

Targeting Mutant p53 by a SIRT1 Activator YK-3-237 Inhibits the Proliferation of Triple-Negative Breast Cancer CellsSemantic proximity Read ↗

MTA1 Promotes STAT3 Transcription and Pulmonary Metastasis in Breast CancerSemantic proximity Read ↗

SIRT3 increases cisplatin sensitivity of small-cell lung cancer through apoptosis.Semantic proximity Read ↗

Metastasis-associated protein (MTA)1 enhances migration, invasion, and anchorage-independent survival of immortalized human keratinocytesSemantic proximity Read ↗

Overexpression of the metastasis-associated gene MTA3 correlates with tumor progression and poor prognosis in hepatocellular carcinoma.Semantic proximity Read ↗

Sirtuin 3 induces apoptosis and necroptosis by regulating mutant p53 expression in small‑cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.