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Article

Functional genetic polymorphisms in cytokines and metabolic genes as additional genetic markers for susceptibility to develop type 1 diabetes.

Genes and immunity - 1 Jan 2004

Eerligh P, Koeleman B P C, Dudbridge F, Jan Bruining G, Roep B O, Giphart M J

Abstract excerpt

Genetic association with type 1 diabetes (T1D) has been established for two chromosomal regions: HLA DQ/DR (IDDM1) and INS VNTR (IDDM2). To identify additional genetic markers, we tested polymorphisms in regulatory regions of several cytokine and important metabolic genes. These polymorphisms exh...

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Source

Identifiers

PMID: 14735147
DOI: 10.1038/sj.gene.6364036

Genes

INS
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14735147-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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