Article
Allelotypic characteristics of thorotrast-induced intrahepatic cholangiocarcinoma: comparison to liver cancers not associated with thorotrast.
Radiation research - 1 Feb 2004
Liu Duo, Wada Ikuo, Tateno Hiroo, Ogino Daisuke, Suzuki Michiko, Li Li, Lu Wang, Kojiro Masamichi, Fukayama Masahisa, Okabe Hiroshi, Fukumoto Manabu
Abstract excerpt
To elucidate the genetic alterations that are specific to Thorotrast-induced liver cancers and their possible roles in tumorigenesis, we analyzed loss of heterozygosity (LOH) at 37 loci. Our previous study of liver cancers that were not associated with Thorotrast found LOH at 9 of these loci to b...
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