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Article

The renal epithelial sodium channel: genetic heterogeneity and implications for the treatment of high blood pressure.

Current pharmaceutical design - 1 Jan 2006

Sagnella G A, Swift P A

Abstract excerpt

The renal epithelial sodium channel (ENaC) is of fundamental importance in the control of sodium reabsorption through the distal nephron. ENaC is an important component in the overall control of sodium balance, blood volume and thereby of blood pressure. This is clearly demonstrated by rare genetic disorders of sodium channel activity (Liddle's Syndrome and Pseudohypoaldosteronism type 1 associated with...

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Identifiers

PMID: 16787251
DOI: 10.2174/138161206777585157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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