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Blood pressure regulation via the epithelial sodium channel: From gene to kidney and beyond

24 May 2013

Abstract excerpt

The epithelial sodium channel (ENaC) has long been recognized as playing a vital role in blood pressure (BP) regulation due to its involvement in fluid balance. The genes encoding the three ENaC subunits are likewise important contributors to hypertension, both in rare monogenic diseases and in the general population. The unusually high numbers of genetic variants associated with complex traits, including BP,...

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Share to Cardiovascular, Neuropeptides, and Oxidative Stress Research
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PMID: 23710770
DOI: 10.1111/1440-1681.12124

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