Article
Confirmation of linkage to chromosome 1q for peak vertebral bone mineral density in premenopausal white women.
American journal of human genetics - 1 Feb 2004
Econs Michael J, Koller Daniel L, Hui Siu L, Fishburn Tonya, Conneally P Michael, Johnston C Conrad, Peacock Munro, Foroud Tatiana M
Abstract excerpt
Peak bone mineral density (BMD) is a highly heritable trait and is a good predictor of the risk of osteoporosis and fracture in later life. Recent studies have sought to identify the genes underlying peak BMD. Linkage analysis in a sample of 464 premenopausal white sister pairs detected linkage of spine BMD to chromosome 1q (LOD 3.6). An independent sample of 254 white sister pairs has now been genotyped, and it...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
