Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear localization of tetrahydrobiopterin biosynthetic enzymes.

Biochimica et biophysica acta - 5 Jan 2004

Elzaouk Lina, Laufs Stephanie, Heerklotz Dirk, Leimbacher Walter, Blau Nenad, Résibois Annette, Thöny Beat

Abstract excerpt

Biosynthesis of the tetrahydrobiopterin (BH(4)) cofactor, essential for catecholamines and serotonin production and nitric oxide synthase (NOS) activity, requires the enzymes GTP cyclohydrolase I (GTPCH), 6-pyruvoyl-tetrahydropterin synthase (PTPS), and sepiapterin reductase (SR). Upon studying t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Oxidoreductases
Share to Biopterins
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to Cytoplasm

Share to GTP Cyclohydrolase

Share to Kidney Tubules

Share to Phosphorus-Oxygen Lyases

Source

Identifiers

PMID: 14729142
DOI: 10.1016/j.bbagen.2003.10.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14729142-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Nuclear localization of tetrahydrobiopterin biosynthetic enzymes.PMID 14729142Read ↗

Retrovirus-mediated double transduction of the GTPCH and PTPS genes allows 6-pyruvoyltetrahydropterin synthase-deficient human fibroblasts to synthesize and release tetrahydrobiopterin.Semantic proximity Read ↗

Subcellular localization of the Huntington's disease gene product in cell lines by immunofluorescence and biochemical subcellular fractionationSemantic proximity Read ↗

Nuclear localization of the G protein beta 5/R7-regulator of G protein signaling protein complex is dependent on R7 binding protein.Semantic proximity Read ↗

Nuclear localization of N-terminal mutant huntingtin is cell cycle dependent.Semantic proximity Read ↗

The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP.Semantic proximity Read ↗

Nuclear-localization-signal-dependent and nuclear-export-signal-dependent mechanisms determine the localization of 5-lipoxygenase.Semantic proximity Read ↗

Chromosomal localization, genomic structure and characterization of the human gene and a retropseudogene for 6-pyruvoyltetrahydropterin synthase.Semantic proximity Read ↗

Dwarfism and low insulin-like growth factor-1 due to dopamine depletion in Pts-/- mice rescued by feeding neurotransmitter precursors and H4-biopterin.Semantic proximity Read ↗

Molecular basis for peroxisomal localization of tetrameric carbonyl reductase.Semantic proximity Read ↗

Subcellular localization of the homocitrate synthase in Penicillium chrysogenum.Semantic proximity Read ↗

Nuclear translocation of ferritin in corneal epithelial cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.