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Article

Molecular mechanisms in calvarial bone and suture development, and their relation to craniosynostosis.

European journal of orthodontics - 1 Apr 2003

Rice David P C, Rice Ritva, Thesleff Irma

Abstract excerpt

The development and growth of the skull is a co-ordinated process involving many different tissues that interact with each other to form a complex end result. When normal development is disrupted, debilitating pathological conditions, such as craniosynostosis (premature calvarial suture fusion) and cleidocranial dysplasia (delayed suture closure), can result. It is known that mutations in the fibroblast growth...

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Source

Identifiers

PMID: 12737212
DOI: 10.1093/ejo/25.2.139

Genes

FGFR1
MSX2
RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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