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Article

Gene amplification as a developmental strategy: isolation of two developmental amplicons in Drosophila.

Developmental cell - 1 Jan 2004

Claycomb Julie M, Benasutti Matt, Bosco Giovanni, Fenger Douglas D, Orr-Weaver Terry L

Abstract excerpt

Gene amplification is known to be critical for upregulating gene expression in a few cases, but the extent to which amplification is utilized in the development of diverse organisms remains unknown. By quantifying genomic DNA hybridization to microarrays to assay gene copy number, we identified two additional developmental amplicons in the follicle cells of the Drosophila ovary. Both amplicons contain genes...

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Identifiers

PMID: 14723854
DOI: 10.1016/s1534-5807(03)00398-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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