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Article

Isolation of CD4-independent primary human immunodeficiency virus type 1 isolates that are syncytium inducing and acutely cytopathic for CD8+ lymphocytes.

Journal of virology - 1 Feb 2004

Zerhouni Bouchra, Nelson Julie A E, Saha Kunal

Abstract excerpt

Previous studies have established the existence of CD4-independent simian immunodeficiency virus, human immunodeficiency virus type 2 (HIV-2), and laboratory strains of HIV-1. However, whether CD4-independent viruses may also exist in HIV-1-infected patients has remained unclear. We have recently reported the isolation of viruses from an AIDS patient that were able to infect CD8(+) cells independent of CD4, using...

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Identifiers

PMID: 14722279
DOI: 10.1128/jvi.78.3.1243-1255.2004
PMCID: PMC321385

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