Article
Isolation and biological characterization of non-B HIV type 1 from Kenya.
AIDS research and human retroviruses - 1 Jul 2012
Muriuki Joseph K, Ngeranwa Joseph N, Mwangi Joseph, Orinda George, Lwembe Raphael, Khamadi Samuel
Abstract excerpt
The isolation and characterization of primary strains of human immunodeficiency virus (HIV) is a vital tool for assessing properties of viruses replicating in HIV-infected subjects. HIV-1 isolation was carried out from 30 HIV-1-infected patients from a Comprehensive Care Clinic (CCC) after informed consent. Virus was successfully isolated from 9 out of the 30 samples investigated. Seven of the isolates were from...
Topics
- Adult
- CD4-Positive T-Lymphocytes
- Cell Line
- Female
- Fluorescent Antibody Technique, Indirect
- Gene Amplification
- HIV Envelope Protein gp120
- HIV Seropositivity
- HIV-1
- Humans
- Kenya
- Male
- Phenotype
- Receptors, CCR5
- Receptors, CXCR4
- Virus Replication
