Article
Family-based association tests for survival and times-to-onset analysis.
Statistics in medicine - 30 Jan 2004
Lange Christoph, Blacker Deborah, Laird Nan M
Abstract excerpt
In this paper, we discuss family-based association test (FBATs) relating genetic data to survival and time-to-onset data. We show how the standard logrank and Wilcoxon statistics can be used with family data to develop tests of association. We prove that the FBAT-logrank approach can be identical to the proportional hazard approach discussed in Mokliatchouk et al. (2000). Further, using simulation studies, we...
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