Article
Targeted mutation of the calbindin D28K gene disrupts circadian rhythmicity and entrainment.
The European journal of neuroscience - 1 Jun 2008
Kriegsfeld Lance J, Mei Dan Feng, Yan Lily, Witkovsky Paul, Lesauter Joseph, Hamada Toshiyuki, Silver Rae
Abstract excerpt
The suprachiasmatic nucleus (SCN) is the principal circadian pacemaker in mammals. A salient feature of the SCN is that cells of a particular phenotype are topographically organized; this organization defines functionally distinct subregions that interact to generate coherent rhythmicity. In Syrian hamsters (Mesocricetus auratus), a dense population of directly retinorecipient calbindin D(28K) (CalB) neurons in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
