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Article

A two-component signal transduction system with a PAS domain-containing sensor is required for virulence of Mycobacterium tuberculosis in mice.

Biochemical and biophysical research communications - 30 Jan 2004

Rickman Lisa, Saldanha José W, Hunt Debbie M, Hoar Dominic N, Colston M Joseph, Millar Jonathan B A, Buxton Roger S

Abstract excerpt

Mycobacterium tuberculosis, the causative organism of tuberculosis, encounters oxidative stress during phagocytosis by the macrophage and following macrophage activation during an acquired immune response, and also from internally generated sources of radical oxygen intermediates through intermed...

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Identifiers

PMID: 14715274
DOI: 10.1016/j.bbrc.2003.12.082
PMCID: PMC2963928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14715274-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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