Article
DNA hybridization in nanostructural molecular assemblies enables detection of gene mutations without a fluorescent probe.
Biomacromolecules - 1 Jan 2000
Maruyama Tatsuo, Park Lian-Chun, Shinohara Toshimitsu, Goto Masahiro
Abstract excerpt
We have developed a simple single nucleotide polymorphisms (SNPs) analysis utilizing DNA hybridization in nanostructural molecular assemblies. The novel technique enables the detection of a single-base mismatch in a DNA sequence without a fluorescent probe. This report describes for the first tim...
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