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DNA hybridization in nanostructural molecular assemblies enables detection of gene mutations without a fluorescent probe.

Biomacromolecules - 1 Jan 2000

Maruyama Tatsuo, Park Lian-Chun, Shinohara Toshimitsu, Goto Masahiro

Abstract excerpt

We have developed a simple single nucleotide polymorphisms (SNPs) analysis utilizing DNA hybridization in nanostructural molecular assemblies. The novel technique enables the detection of a single-base mismatch in a DNA sequence without a fluorescent probe. This report describes for the first time that DNA hybridization occurs in the nanostructural molecular assemblies (termed reverse micelles) formed in an...

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PMID: 14715007
DOI: 10.1021/bm034047z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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