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Article

Predisposition to alcoholism, tryptophan oxygenase activity, and structure of intron 6 in the corresponding gene of C57BL/6J, CC57BR/Mv, and BALB/cJ mice.

Bulletin of experimental biology and medicine - 1 Oct 2003

Kaledin V I, Klimova N V, Vasil'ev G V, Ivanova E A, Vasil'eva E D, Il'nitskaya S I

Abstract excerpt

Crossbred CC57BR/Mv mice inherited tryptophan oxygenase gene and predisposition to alcohol consumption from parent BALB/c and C57BL mice, respectively. In CC57BR/Mv mice no relationships were found between alcohol consumption, tryptophan oxygenase activity, and single nucleotide substitutions in intron 6 of the TDO2 gene associated with predisposition to alcoholism in humans.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14714090
DOI: 10.1023/b:bebm.0000010959.61321.3b

Genes

TDO2

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