Article
The human indoleamine 2,3-dioxygenase gene and related human genes.
Current drug metabolism - 1 Apr 2007
Murray Michael F
Abstract excerpt
Tryptophan oxidation occurs via both extra-hepatic and hepatic pathways. Although these pathways share many enzymes, the first and rate-limiting step in each pathway is carried out by two different enzymes: Indoleamine-Pyrrole 2,3 Dioxygenase (INDO) and Tryptophan 2,3-Dioxygenase (TDO2). Over the course of the last forty years extensive and detailed research by many groups have led to an understanding of some of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
